I didn't know it turned out so good, and it was a funny movie." Garofalo had been David Fincher's first choice for the role of Marla Singer in the film Fight Club, but she turned it down, uncomfortable with the film's unusual sexual content (Fincher later noted that she was "uncomfortable with the idea of all this sex”), and Helena Bonham Carter eventually accepted the part.Following up the successful The Truth About Cats and Dogs in 1996, Garofalo played the leading role in the The Matchmaker, a 1997 romantic comedy film about the misadventures of a cynical American woman who reluctantly visits Ireland.

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Garofalo has performed a variety of leading, supporting and cameo roles in more than 50 feature films, playing leading or large roles in Reality Bites, The Truth About Cats and Dogs, I Shot a Man in Vegas, The Matchmaker, Clay Pigeons, Steal This Movie!

, Sweethearts, Mystery Men, The Independent, Wet Hot American Summer, Manhood, Ash Tuesday, and Bad Parents, among others, and supporting roles in The Cable Guy, Romy and Michele's High School Reunion, Cop Land, Half Baked, Permanent Midnight, Dogma, and The Wild.

The following year, Garofalo was top-billed in Wet Hot American Summer, the 2001 cult comedy about a Jewish summer camp, and starred in The Search for John Gissing.

In 2002, she played Catherine Connolly in The Laramie Project and in 2003, she starred in Manhood and Ash Tuesday, and appeared in the crime film Wonderland.

She played a supporting role in Jiminy Glick in Lalawood in 2004.

A puppet version of Garofalo appeared (and was graphically killed off) in the 2004 movie Team America: World Police; while Garofalo was irritated by the parody, she was more upset by the filmmaker's lack of correspondence., Clay Pigeons, Sweethearts, Mystery Men, and The Independent, among numerous others.She has also been a series regular on television programs such as Wet Hot American Summer: First Day of Camp, 24, and Girlfriends' Guide to Divorce. From March 2004 to July 2006, she hosted Air America Radio's The Majority Report with Sam Seder.; born September 28, 1964) is an American actress, stand-up comedian, liberal political activist, and writer.Garofalo began her career as a stand-up comedian and became a cast member on the The Ben Stiller Show, The Larry Sanders Show, and Saturday Night Live, then appeared in more than 50 movies, with leading or major roles in The Truth About Cats and Dogs, Wet Hot American Summer, The Matchmaker, Reality Bites, Steal This Movie!In 1999, she starred as "The Bowler" in the film Mystery Men, about an underdog group of super heroes.